Cochrane Reviews are systematic reviews of primary research in human health care and health policy, and are internationally recognised as the highest standard in evidence-based health care. They may either investigate the effects of interventions for prevention, treatment, and rehabilitation, or alternatively may assess the accuracy of a diagnostic test for a given condition in a specific patient group and setting. A unique feature of Cochrane Reviews is that they are living documents in that they are updated with new evidence that emerges. They were conceived as electronic publications from the outset, and designed to take advantage of features unique to electronic publishing.